Skip to main content
Dr. GreenthumbDR.GREENTHUMB
AboutMediaLicensingStrainsStoreLocationsLearnLegal LibraryContact

GET THE GREENTHUMB NEWSLETTER

New drops, B-Real updates, and whatever else we feel like sharing. No spam.

Dr. GreenthumbDR.GREENTHUMB

Est. 1993. Before it was legal.

Company

  • About Us
  • B-Real
  • Media
  • Licensing
  • Contact

Learn

  • Beginner's Guide
  • How It's Made
  • All Articles
  • Cannabis Legal Guide
  • Legal Library

Locations

  • Find a Store
  • Our Locations
  • Strains
  • Shop

Legal

  • Privacy Policy
  • Terms of Service
  • Editorial Policy
  • Accessibility
  • Do Not Sell My Info

21+ Only: For use only by adults 21 years of age or older. Keep out of reach of children. Do not drive a motor vehicle while under the influence of cannabis. Licensed dispensary. California and Illinois licenses displayed at each location.

© 2026 Dr. Greenthumb. All rights reserved.

Sitemap

Disclaimer: Cannabis affects everyone differently. Individual experiences may vary.

Cannabinoids 101: THC, CBD, CBG, and Beyond
Education

CANNABINOIDS 101: THC, CBD, CBG, AND BEYOND

By Pedro Garcia·April 18, 2026·Updated July 18, 2026·6 min read
  1. Home
  2. /
  3. Learn
  4. /
  5. Cannabinoids 101: THC, CBD, CBG, and Beyond
Cannabinoids 101: THC, CBD, CBG, and Beyond

The cannabis plant contains over 100 cannabinoids. Here's what each one does, how they interact with your body's endocannabinoid system, and why the entourage effect matters.

IN THIS ARTICLE

  • The Entourage Effect: Why Numbers Don't Tell Everything
  • THC: The Heavyweight Champion
  • THCA vs THC: The Raw Truth
  • CBD: The Balancing Act
  • The CBD Market Reality
  • CBG: The Mother Cannabinoid
  • The Minor League All-Stars
  • CBC (Cannabichromene)
  • CBN (Cannabinol)
  • THCV (Tetrahydrocannabivarin)
  • Terpenes: The Supporting Cast That Steals the Show
  • Myrcene: The Couch Lock Molecule
  • Limonene: Citrus Clarity
  • Caryophyllene: The Spicy Exception
  • Reading Lab Reports: What Actually Matters
  • The Future: What's Coming Next
  • Beyond the Buzz: Practical Applications
  • The Dr. Greenthumb's Difference
  • Related Reading

THC gets all the attention, but there are over 100 cannabinoids in the cannabis plant. Each one interacts with your body differently.

Walk into our La Mesa location on any given Tuesday, and you'll hear the same questions. "What's the THC percentage?" "Does this have CBD?" "Why does this strain cost more if it's only 18% THC?" These aren't bad questions — they're just incomplete ones.

Here's what 30 years in cannabis has taught us: chasing THC numbers is like judging wine by alcohol content alone. You're missing the whole story.

The Entourage Effect: Why Numbers Don't Tell Everything

The entourage effect isn't just dispensary talk — it's real science. Cannabinoids work together, not in isolation. A 32% THC strain might feel weaker than a 24% strain because of how the other cannabinoids interact.

Our Insane OG consistently tests between 28-32% THC, but customers at our Fresno store don't just buy it for the numbers. They come back because of how it feels — and that's where the other cannabinoids come in.

THC: The Heavyweight Champion

Delta-9-tetrahydrocannabinol. The cannabinoid that launched a thousand prohibition laws and just as many late-night convenience store runs.

THC binds directly to CB1 receptors in your brain and CB2 receptors throughout your body. It's responsible for cannabis's psychoactive effects — that elevated feeling that's kept people coming back for centuries.

But here's where it gets interesting. THC percentages don't tell you everything about potency. A 20% THC strain with high myrcene levels (think Granddaddy Purple lineage) might feel more sedating than a 28% THC sativa-dominant strain loaded with limonene.

At our Canoga Park location, we've noticed customers are getting smarter about this. They're not just asking for "the strongest stuff" anymore. They're asking about terpene profiles and effects.

THCA vs THC: The Raw Truth

Most lab reports show THCA, not THC. THCA is the non-psychoactive precursor that converts to THC when heated. Raw cannabis won't get you high — it needs decarboxylation through smoking, vaping, or cooking.

The conversion isn't perfect. When labs report 25% THCA, you're looking at roughly 22% THC after decarboxylation. Those numbers matter when you're calculating dosages for edibles or tinctures.

CBD: The Balancing Act

Cannabidiol changed everything. Before CBD hit mainstream awareness around 2014, cannabis was either "medical" or "recreational." CBD blurred those lines permanently.

CBD doesn't bind directly to cannabinoid receptors like THC does. Instead, it works more subtly — influencing how other compounds interact with your endocannabinoid system. Think of it as a moderator in a heated discussion, keeping things balanced.

Our budtenders at the Orcutt store report that customers often ask for "high CBD strains" without understanding ratios. A 1:1 THC:CBD strain (like our Harlequin cut that tests around 8% THC and 9% CBD) feels completely different from a 20:1 CBD strain.

The CBD Market Reality

Here's something they don't tell you in CBD marketing: most hemp-derived CBD products contain virtually no other cannabinoids or terpenes. Cannabis-derived CBD, like what we carry in our South Holland location, includes the full spectrum of compounds that work together.

The difference is noticeable. Hemp CBD isolate might help with general wellness, but cannabis-derived CBD with minor cannabinoids and terpenes offers what customers describe as a more "complete" experience.

CBG: The Mother Cannabinoid

Cannabigerol doesn't get headlines, but it should. CBG is the precursor to THC, CBD, and CBC. In young cannabis plants, most cannabinoids exist as CBGA (CBG acid). As the plant matures, enzymes convert CBGA into other cannabinoids.

Most strains contain less than 1% CBG because it's been converted to other compounds. But some phenotypes — particularly certain White Widow and Jack Herer lines — maintain higher CBG levels even at harvest.

Customers at our Fresno location who specifically seek CBG strains often mention feeling more focused without the anxiety that high-THC strains sometimes produce. We carry a few CBG-dominant strains that test between 8-12% CBG with minimal THC.

The Minor League All-Stars

CBC (Cannabichromene)

CBC doesn't bind well to CB1 or CB2 receptors, but it interacts with other receptor systems. It's often found alongside CBD in balanced strains. Our Cannatonic phenotype typically shows 2-4% CBC alongside its 6% CBD and 4% THC profile.

CBN (Cannabinol)

CBN forms when THC degrades over time. Aged cannabis, improperly stored flower, or certain curing techniques increase CBN levels. Many customers associate CBN with sedation, though the research is still developing.

We've noticed that some of our older inventory — properly stored but aged 8-10 months — tests higher in CBN. These batches often appeal to customers looking for evening strains.

THCV (Tetrahydrocannabivarin)

THCV is found in higher concentrations in African landrace strains like Durban Poison. It's structurally similar to THC but may produce different effects, especially at lower doses.

Some Durban Poison phenotypes we've carried at our La Mesa store test around 2-3% THCV alongside 18-22% THC. Customers report a cleaner, more energetic experience compared to typical indica-dominant strains.

Terpenes: The Supporting Cast That Steals the Show

Terpenes aren't cannabinoids, but they work so closely together that separating them doesn't make sense. Every time someone walks into our Canoga Park location and says a strain "smells like lemons" or "tastes like pine," they're talking about terpenes.

Myrcene: The Couch Lock Molecule

Myrcene is the most common terpene in cannabis, especially indica-dominant strains. Concentrations above 0.5% are associated with more sedating effects. Our Granddaddy Purple typically shows 0.8-1.2% myrcene, which explains why customers buy it for evening use.

Limonene: Citrus Clarity

Limonene gives strains like Sour Diesel their characteristic citrus aroma. It's found in lemon peels, orange rinds, and certain cannabis chemotypes. Strains high in limonene often appeal to customers looking for daytime options.

Our Insane OG shows significant limonene content — usually 0.6-0.9% — combined with caryophyllene around 0.4-0.7%. That combination creates the strain's distinctive profile that keeps customers coming back.

Caryophyllene: The Spicy Exception

Caryophyllene is unique among terpenes because it also acts as a cannabinoid, binding to CB2 receptors. It's found in black pepper, cloves, and many OG Kush lineage strains.

Strains with high caryophyllene content (above 0.5%) often have that spicy, peppery finish that experienced smokers recognize immediately.

Reading Lab Reports: What Actually Matters

Every product in our stores comes with a Certificate of Analysis (COA). Here's what to look for:

Total Active Cannabinoids: This includes THC, CBD, CBG, CBC, CBN, and others. A strain with 25% THC and 2% other cannabinoids hits differently than one with 25% THC and no supporting cast.

Terpene Profile: Look for strains with total terpene content above 1%. The individual terpenes matter more than the total, but strong terpene profiles generally indicate quality cultivation and processing.

Harvest Date: Cannabinoids and terpenes degrade over time. Flower harvested 3-4 months ago will have different profiles than the same genetics harvested 10 months ago.

The Future: What's Coming Next

Research into minor cannabinoids is accelerating. THCP, discovered in 2019, appears to bind to CB1 receptors more effectively than THC. Delta-8 THC offers a different experience than traditional delta-9 THC.

But here's the thing — cannabis worked for thousands of years before we knew what cannabinoids were. The plant developed these compounds through evolution, not market research.

Beyond the Buzz: Practical Applications

Understanding cannabinoids helps you make better choices. Looking for something energizing? Consider strains with THCV and limonene. Want something for evening use? Look for myrcene and CBN. Need to stay functional during the day? Balanced THC:CBD ratios might work better than high-THC options.

Our customers at the Orcutt location have caught on to this. They're asking for specific terpene profiles and cannabinoid ratios, not just "your strongest indica."

The Dr. Greenthumb's Difference

After 30 years, we've learned that great cannabis isn't about one number — it's about the symphony. Our Insane OG works because THC, terpenes, and minor cannabinoids create something greater than the sum of their parts.

Every strain we carry gets tested not just for potency, but for the complete cannabinoid and terpene profile. Because when B-Real started growing in 1988, he wasn't chasing THC percentages. He was chasing the perfect high.

The cannabis plant produced over 100 cannabinoids for a reason. We're just beginning to understand why.

Related Reading

  • Cannabis Legal Guide: Know the Law in Every State
  • The Evolution of Cannabis Seeds: From Landrace to Modern Genetics
  • Resin vs Rosin: Cannabis Concentrates Explained
  • Minor Cannabinoids: The Science Behind CBG, CBN, and THCV
PG

Written by

Pedro Garcia

Cannabis Content Director

Pedro Garcia is the Cannabis Content Director at Dr. Greenthumb's, where he leads the editorial team covering cannabis science, strain genetics, and West Coast culture. With deep roots in California's cannabis industry and years spent visiting grows, attending trade shows, and working alongside the DGT retail team, Pedro brings firsthand knowledge to every piece he writes. He's spent time in the fields at Desert Hot Springs, walked the floors at Hall of Flowers and MJBizCon, and talked shop with breeders whose selection work spans decades. His writing focuses on what he's seen, tested, and learned — not what he's read secondhand.

MORE TO READ

Featured image for How THC Gummies Are Manufactured, Step by Step

HOW THC GUMMIES ARE MANUFACTURED, STEP BY STEP

A behind-the-scenes look at THC gummy manufacturing — from emulsifying distillate to depositing, drying, and dusting the finished pieces you find on the shelf.

Featured image for Shelf Stability: The Chemistry of Why Gummies Degrade

SHELF STABILITY: THE CHEMISTRY OF WHY GUMMIES DEGRADE

Cannabis gummies don't last forever. Understanding the science behind THC degradation, oxidation, and proper storage can help preserve your edibles' potency and flavor.

Featured image for Why Edibles Hit Differently: The Science Behind the High

WHY EDIBLES HIT DIFFERENTLY: THE SCIENCE BEHIND THE HIGH

Ever wonder why that gummy knocked you on your ass? The answer lies in your liver and a compound called 11-hydroxy-THC.

Shop the lineup

Dr. Greenthumb's edibles & gummies

Lab-tested gummies and edibles from B-Real's brand — dosed, compliant, and made for adults 21+.

Keep exploring →
Find Dr. Greenthumb's Near You
Back to Learn